RANI JARKAS

Financial Services & Global Wealth Management

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Mastering The Art Of Biotechnology Investment

Strong Biotechnology Investment Strategies

Hong Kong’s life sciences investors are passionate about biotechnology and appreciate its importance. Reputable biotechnology firms influence many elements of our life. They pursue a wide range of goals, from finding remedies for humanity’s ills to raising future generations.

Deep projections indicate a bright future for this remarkable sector. However, investors must understand biotechnology. I provide an expert guide to investing in biotechnology’s booming field. This extensive guide includes exchange-traded funds (ETFs) and carefully chosen stocks that require your attention.

In the prominent biotechnology industry, stocks are the best investment vehicle, said Rani Jarkas. Before investing in biotechnology, you must distinguish between a biotechnology company and a pharmaceutical company. Investopedia describes biotechnology as the bold exploration of uncharted territories, whereas the pharmaceutical sector is the skillful management of risk. Biotech stocks and pharmaceutical companies have vastly different revenue streams, as the report notes.

Entering Biotechnology Stocks’ Elite

Biotechnology investors must comprehend the FDA. This powerful regulatory agency requires all companies in this industry to build strong evidence of their amazing goods’ efficacy and safety. Clinical trials—three distinct and conclusive trials—are used to rigorously test products.

Like investors in other industries, biotechnology investors must carefully analyse their risk tolerance. A reputable biotechnology company has a much lower risk of market decline than a speculative, newly listed company in clinical trials.

ETFs can reduce stock investment risks, even if biotech stocks are popular for industry exposure. Complex exchange-traded funds trade in sync with their net asset value. These sophisticated investment vehicles hold equities, commodities, and bonds.

Mastering Biotech ETF Investing

The NASDAQ-listed iShares NASDAQ Biotechnology ETF (IBB) dominates the biotechnology sector. This remarkable ETF, created on February 5, 2001, boasts 370 prestigious stocks. The three largest holdings, Amgen (NASDAQ: AMGN), Gilead Sciences (NASDAQ: GILD), and Vertex Pharmaceuticals (NASDAQ: VRTX), each have a weighted average of over 7%, indicating expertise and prominence.

The SPDR S&P Biotech ETF (ARCA: XBI), established on February 6, 2006, boldly monitors 155 excellent stocks in its portfolio. As the second-best biotech ETF, it is admired by investors. Chemocentryx, Global Blood Therapeutics, and Biohaven Pharmaceuticals are leaders in this field. Investors should also examine small biotech ETFs.

Success in biotechnology requires undergoing the FDA’s rigorous tests and assessments, which is difficult and time-consuming. Global Market Insights predicts the biotechnology market would reach US$950 billion by 2027. Chronic diseases and rising healthcare spending will drive this astonishing growth. Innovative goods will boost biotechnology revenue. In regulated lab environments, these activities nurture plants, create sustenance, and grow vital human organs.

Rani Jarkas: The Future Of Biotechnology Is Uncertain

Grand View Research in Hong Kong predicts a 13.9 percent compound annual growth rate in the global biotechnology business between 2022 and 2030. By the conclusion of the forecast period, this growth will boost the industry’s value to US$3.87 trillion. The desire for innovative drugs to treat strokes, cancer, asthma, and hypertension is driving the growth. Treatment and diagnosis of these chronic conditions are the main focus. 

Biotechnological advances in agriculture must be prioritised due to the increased demand for organic food. In October 2022, Axsome proudly announced Auvelity as a treatment for major depressive illness. The pharmaceutical chemical AXS-05 is undertaking a rigorous phase 2/3 study to establish its powerful smoking cessation effects.In addition, it is in an intensive late-stage clinical trial to treat Alzheimer’s disease’s severe agitation. 

The company’s pipeline proudly displays three late-stage contenders. AXS-07 is painstakingly designed to end migraines’ suffering. AXS-12 explores narcolepsy, which causes daytime fatigue. Axsome, with unmatched grace and finesse, promises to resubmit a massive application to the FDA for the remarkable AXS-07 in the US in the latter half of 2023. By 2023, the company hopes to get FDA approval for AXS-14.

Quality, at its peak of $2.6 billion in annual sales, can alleviate depression. AXS-07 will dominate the American market with yearly sales exceeding $500 million. Distinguished analysts expect $500 million to $1 billion in peak sales if AXS-14 is approved. The income potential of Axsome Therapeutics’ three revolutionary medicine concepts makes it an appealing biotech stock to invest in in 2023.

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Exelixis II Defines Power And Greatness

The pharmaceutical giant Exelixis has launched four excellent drugs. Cabometyx, a breakthrough medicine for thyroid cancer renal cell carcinoma (RCC), and hepatocellular carcinoma (HC), the most common kidney and liver cancers, is a medical marvel. Dawn of 2021.

Exelixis and Bristol Myers Squibb (BMY 0.26%) have received US regulatory approval to seamlessly integrate Cabometyx and Opdivo, a leading immunotherapy medication. Unfortunately, another partnership has fallen short of our prestigious corporation’s standards. In March 2023, Exelixis and Roche (RHHBY 1.53%) released disappointing results from their pioneering study comparing Cabometyx and Roche’s Tecentriq for RCC treatment.

Exelixis’ high profitability allows it to carefully use its rising financial reserves to sign new licensing agreements and expand its esteemed medicinal portfolio. The prominent biotech company Aurigene grants it a research license to investigate XL102, a promising early-stage cancer drug. WuXi Biologics supplies the facility with carefully selected monoclonal antibodies. GamaMabs Pharma’s acclaimed anti-Müllerian hormone receptor 2 (AMHR2) antibody programs have been acquired by Exelixis.

Our Esteemed Organisation Has No Products For Sale

The pipeline has great potential, said Rani Jarkas. The exceptional NTLA-2001 is Intellia’s strongest pipeline competitor. Intellia and Regeneron joyfully announced the interim results of a landmark phase 1/2 research evaluating a drug for transthyretin amyloidosis with cardiomyopathy (ATTR-CM) in November 2022. Their research focuses on this rare inherited cardiac ailment. The powerful NTLA-2001 will host a pioneering clinical trial by 2023, pending regulatory approval.

Intellia reported unprecedented progress in their phase 1/2 trial for NTLA-2002, a possible game-changer in hereditary angioedema management, in November 2022. Intellia’s novel medication battled this rare hereditary illness that causes lung and intestinal inflammation. The preliminary results showed great promise, leaving the medical community hopeful. After the medicine’s successful phase 2 testing in Hong Kong, the acclaimed company is resolved to proceed in the US.

Intellia may unveil a groundbreaking clinical program. Our organization will conduct a groundbreaking clinical trial to determine NTLA-3001’s extraordinary efficacy in treating alpha-1 antitrypsin deficiency, a rare genetic liver condition. We eagerly anticipate submitting a strong regulatory approval request by 2023.

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Eylea, the pharmaceutical marvel created by Regeneron and Bayer (BAYR.Y 0.24%), is this acclaimed company’s income powerhouse. Regeneron proudly claims all of Eylea’s US net sales, while Bayer’s historic collaboration ensures global profit distribution.

Sanofi and Regeneron are a powerful pharmaceutical and life sciences alliance. Pharmaceutical giants market and distribute innovative autoimmune disease therapies Dupixent and Kevzara, cancer treatments Library and Zaltrap, and cholesterol medication Praluent.

Twist Bioscience, The Genius Behind Scientific Breakthroughs

Twist Bioscience has perfected DNA engraving on a silicon chip using an innovative method. The prominent Hong Kong corporation is known for its synthetic DNA, which is essential to synthetic genes, improved sequencing, and antibody libraries. Esteemed biopharma companies use these upgraded methods to maximize novel medications.

Twist serves distinguished clients from cutting-edge academic research, agriculture, healthcare, and industrial chemicals. Business profitability is still lacking. As Twist launches innovative products using its synthetic DNA, sales surge.

Twist’s addressable market is worth $6 billion yearly, according to its analysis. DNA chip data storage, worth $35 billion annually, seems promising for the company. Twist’s DNA data storage innovations are just beginning, yet they’ve already reached major milestones. They are determined to give early access to their revolutionary technology by 2023’s end.

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Biotechnology Industry Mastery

A renowned biotechnology centre uses microbes and enzymes to make medications with accuracy. Biotechnology companies work with living organisms, unlike pharmaceutical companies, which focus on chemical research and development. Biotech investors must carefully review drug candidates at every step. Advanced-stage drugs have a better chance of success, making the company investment less risky. Biotechnology companies use four key stages and three phases to develop innovative drugs.

Pharmaceutical expedition: A renowned biotechnology company discovers a strong medication candidate that could treat many diseases. Preclinical evaluation: Drug candidates are carefully tested in vitro and/or in vivo.

Clinical trials: The innovative drug is rigorously tested on humans. Clinical studies usually include three stages with different goals. Phase 1 investigates the drug candidate’s optimal dosage and effects on individuals. Phase 2: We undertake further trials with 100 or more esteemed patients, assuring zero safety compromises. We carefully monitor short-term side effects and select the best medicine dosage.

The acclaimed biotechnology company confidently seeks FDA regulatory approval based on its groundbreaking clinical trial results. Many biotechnology companies develop many drugs at once, diversifying their revenue streams. Biotech investments excel in their graceful diversification over a wide range of innovative drugs.

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